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VIAGRA [Sildenafil citrate] An Overview
VIAGRA [Sildenafil citrate] is the only approved and effective oral agent for the treatment of erectile dysfunction. Before that a few lines on erectile dysfunction. Erectile dysfunction [Impotence] is a condition in which erection the penis cannot be achieved during sexual intercourse/masturbation. There are many causes for erectile dysfunction. The most common cause of being increasing age. Other conditions can be: - Diabetes Mellitus - Hypertension - Heart Disease - Atherosclerosis - Lower spinal cord injury - Cancer prostate - Psychogenic - Stress Erection is achieved when there is increased blood flow to penis and hence the main organic cause is disturbance of blood flow to and from the penis. Coming back to VIAGRA [Sildenafil citrate], Viagra is a selective and potent inhibitor of cyclic guanosine monophosphate [cGMP] specific phosphodiesterase type 5 inhibitor [PDE5] which is the predominant phosphodiesterase isoform found in the penis. It is administered in doses of 25, 50 and 100 mg, and enhances erection after sexual stimulation. The onset of action is around 60-90 mins. Sildenafil (compound UK-92,480) was synthesized by a group of chemists working at Pfizer's Sandwich, Kent research facility in England. It was initially studied for use in hypertension and angina pectoris. The first clinical trials were conducted in Morriston Hospital in Swansea. Phase I clinical trials under the direction of Ian Osterloh suggested that the drug had little effect on angina, but that it could induce marked penile erections. VIAGRA [Sildenafil citrate] was approved for use in erectile dysfunction by the Food and Drug Administration on March 27, 1998, becoming the first pill approved to treat erectile dysfunction Reduced initial doses should be considered for patients, who are elderly, have renal insufficiency, or are taking medications that inhibit the CYP3A4 metabolic pathway in the liver [e.g., erythromycin, cimetidine, ketoconazole] as they may increase the serum concentration of sildenafil. The drug does not affect ejaculation, orgasm or sexual drive. When sexual stimulation causes local release of NO, inhibition of PDE5 by VIAGRA [Sildenafil citrate] causes increased levels of cGMP in the corpus cavernosum of the penis resulting in smooth muscle relaxation and inflow of blood to the corpus cavernosum. Side Effects: ?? Headaches ?? Facial flushing ?? ringing in ears, or sudden hearing loss ?? Dyspepsia ?? Nasal congestion. ?? Abnormal vision [blue halo effect] ?? Diarrhea ?? Dizziness ?? Rashes Viagra can decrease blood flow to the optic nerve of the eye, causing sudden vision loss:- Special precautions: In patients with ?? Bleeding disorders such as hemophilia ?? Liver disorder ?? Kidney disorder ?? Active peptic ulcerations and ?? Anatomical deformation of the penis, such as peyronie's disease. ?? Retinitis pigmentosa Contraindications: VIAGRA [Sildenafil citrate], is contraindicated in men receiving nitrate therapy for cardiovascular disease, including agents delivered by oral, sublingual, trans-nasal or topical routes. These agents can potentates its hypotensive effect and may result in profound shock. Viagra should be avoided in patients with congestive heart failure and cardiomyopathy because of the risk of vascular collapse.
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We provide online drugs, such as viagra, sildenafil citrate for Erectile Dysfunction(ED) Medication. Also Learn About Erectile Dysfunction and VIAGRA, an ED Treatment Option, we offer Viagra online prescription medications and more. Buy Viagra from the internet's leading online pharmacy at low prices. Generic Viagra is a performance enhancing drug used by people suffering from erectile... 
People have this general notion that impotence, or more appropriately termed as erectile dysfunction, is only for older men. This is partly true. Statistics show that most American men between ages 40 and 70 experience impotence to some degree each year. An estimated 15 million to 30 million men in the U.S. experience erectile dysfunction. However, impotence can also afflict younger people due...
Erectile dysfunction (ED) is when you have trouble getting or keeping an erection. Erectile Dysfunction advice and solutions tag, as close to the beginning of it as possible. Erectile Dysfunction (ED) is a common condition, 40% of men over 40 suffer from some degree of erection problem. Erectile dysfunction or ED is the inability to achieve or sustain an erection suitable for sexual...
In a life span of people suffering from lots of problems, so obviously they will think about those problems. And then the possible out come of those problems is stress and depression or they may addict to alcohol or any other harmful drugs. Some people making smoking habitual to get relief, interim they can feel relax for sometime but that will affect to health. Young people may feel anxiety for...
Erectile dysfunction is a state of men wherein they lack the ability to sustain erection that is needed during intercourse. Thus, the people who have this kind of sexual problem would like to find the safe and best erectile dysfunction medicine available.
There can be various causes for this kind of ailment and it can be physical, mental, or emotional problems that led to erectile dysfunction....
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